Nesfatin-1 alleviates gastric damage via direct antioxidant mechanisms


Kolgazi M. , Cantali-Ozturk C., Deniz R., ÖZDEMİR KUMRAL Z. N. , YÜKSEL M., ŞİRVANCI S., ...Daha Fazla

JOURNAL OF SURGICAL RESEARCH, cilt.193, ss.111-118, 2015 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 193 Konu: 1
  • Basım Tarihi: 2015
  • Doi Numarası: 10.1016/j.jss.2014.06.057
  • Dergi Adı: JOURNAL OF SURGICAL RESEARCH
  • Sayfa Sayıları: ss.111-118

Özet

Background: Indomethacin is a nonsteroidal anti-inflammatory drug, which is known to produce serious side effects, causing ulcerative lesions. Nesfatin-1, a newly identified anorexigenic peptide, was recently shown to have neuroprotective effects. The aim of the study was to investigate the anti-inflammatory effects of nesfatin-1 on indomethacin-induced gastric ulcer.