The effects of a novel non-invasive application of platelet-rich fibrin on periodontal clinical parameters and gingival crevicular fluid transforming growth factor-beta and collagen-1 levels: A randomized controlled clinical study

Ozcan E., Saygun I., Kantarci A., Ozarslanturk S., SERDAR M. A., Ozgurtas T.

JOURNAL OF PERIODONTOLOGY, cilt.92, sa.9, ss.1252-1261, 2021 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 92 Sayı: 9
  • Basım Tarihi: 2021
  • Doi Numarası: 10.1002/jper.20-0713
  • Dergi Adı: JOURNAL OF PERIODONTOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, BIOSIS, CAB Abstracts, CINAHL, EMBASE, MEDLINE, Veterinary Science Database, DIALNET
  • Sayfa Sayıları: ss.1252-1261
  • Anahtar Kelimeler: collagen-type1, gingival crevicular fluid, platelet-rich fibrin, regeneration, root planing, transforming growth factor beta
  • Acıbadem Mehmet Ali Aydınlar Üniversitesi Adresli: Evet

Özet

Background Several potential benefits have been attributed to the platelet-rich fibrin (PRF), including enhanced tissue healing properties. In this study, we hypothesized that the application of PRF as an adjunct to conventional scaling and root planing (ScRp) would enhance the outcomes of non-surgical periodontal therapy.