Memory Function and Total Pyramidal Neuron Number of Hippocampus in Streptozotocin-induced Diabetic Rats

Yonguc G. N., Ozdemir M. B., Kucukatay V., ŞAHİNER A. M., AKCILAR R., Adiguzel E., ...Daha Fazla

JOURNAL OF NEUROLOGICAL SCIENCES-TURKISH, cilt.31, sa.3, ss.461-473, 2014 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 31 Sayı: 3
  • Basım Tarihi: 2014
  • Dergi Adı: JOURNAL OF NEUROLOGICAL SCIENCES-TURKISH
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.461-473
  • Anahtar Kelimeler: Hippocampus, Diabetes, Memory impairment, Stereology, Optical fractionator method, Morris Water Maze, SYNAPTIC PLASTICITY, DEMENTIA, PERFORMANCE, IMPAIRMENT, MELLITUS, INSULIN, STRESS, RISK
  • Acıbadem Mehmet Ali Aydınlar Üniversitesi Adresli: Evet

Özet

Introduction: Cognitive impairments caused by diabetes mellitus are well documented by previous studies. The studies about neuronal deficits and cognitive impairments in animal models of diabetes mellitus do not simultaneously indicate the total neuron number in the brain subfields and cognitive test performance. In this study, we simultaneously demonstrated total pyramidal neuron number of hippocampus and water maze test performance in streptozotocin-induced diabetic rats.