Increased Serum Nesfatin-1 Levels in Patients with Impaired Glucose Tolerance


Akin S., Gulcelik N. E. , Aksoy D. Y. , KARAKAYA KARABULUT J., Usman A.

TURKISH JOURNAL OF ENDOCRINOLOGY AND METABOLISM, cilt.21, ss.65-67, 2017 (ESCI İndekslerine Giren Dergi)

  • Cilt numarası: 21 Konu: 3
  • Basım Tarihi: 2017
  • Doi Numarası: 10.25179/tjem.2017-56543
  • Dergi Adı: TURKISH JOURNAL OF ENDOCRINOLOGY AND METABOLISM
  • Sayfa Sayısı: ss.65-67

Özet

Purpose: Nesfatin-1 is a recently discovered energy-regulating peptide, widely expressed in both central and peripheral tissues. It is involved in various functions, such as the stimulation of hypothalamic-pituitary-adrenal axis and sympathetic nervous system, influencing visceral functions, water intake, and regulation of temperature and emotions. It exerts a direct glucose-dependent insulinotropic action on the beta cells of pancreatic islets. The current study evaluated nesfatin-1 levels and insulin response to glucose load in patients with impaired glucose tolerance (IGT) and in healthy subjects.