Clinical chemistry, vol.67, pp.1259-1270, 2021 (Journal Indexed in SCI)
Article / Article
Title of Journal :
biological variation, within-subject biological variation, analytical performance specification, Bayesian model, reference change value, D-DIMER, DISTRIBUTIONS, PROJECT, PHASE, TIME
BACKGROUND: For biological variation (BV) data to be safely used, data must be reliable and relevant to the population in which they are applied. We used samples from the European Biological Variation Study (EuBIVAS) to determine BV of coagulation markers by a Bayesian model robust to extreme observations and used the derived within-participant BV estimates [CVP(i)] to assess the applicability of the BV estimates in clinical practice.