The European Biological Variation Study (EuBIVAS): Biological Variation Data for Coagulation Markers Estimated by a Bayesian Model.


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Aarsand A. K., Kristoffersen A. H., Sandberg S., Støve B., Coşkun A., Fernandez-Calle P., ...Daha Fazla

Clinical chemistry, cilt.67, ss.1259-1270, 2021 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 67
  • Basım Tarihi: 2021
  • Doi Numarası: 10.1093/clinchem/hvab100
  • Dergi Adı: Clinical chemistry
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, BIOSIS, Biotechnology Research Abstracts, CAB Abstracts, Chemical Abstracts Core, Chimica, CINAHL, EMBASE, MEDLINE, Veterinary Science Database
  • Sayfa Sayıları: ss.1259-1270
  • Anahtar Kelimeler: biological variation, within-subject biological variation, analytical performance specification, Bayesian model, reference change value, D-DIMER, DISTRIBUTIONS, PROJECT, PHASE, TIME
  • Acıbadem Mehmet Ali Aydınlar Üniversitesi Adresli: Evet

Özet

BACKGROUND: For biological variation (BV) data to be safely used, data must be reliable and relevant to the population in which they are applied. We used samples from the European Biological Variation Study (EuBIVAS) to determine BV of coagulation markers by a Bayesian model robust to extreme observations and used the derived within-participant BV estimates [CVP(i)] to assess the applicability of the BV estimates in clinical practice.