Structural characterization of recombinant bovine Go alpha by spectroscopy and homology modeling
SPECTROSCOPY-BIOMEDICAL APPLICATIONS, cilt.26, sa.4-5, ss.213-229, 2011 (SCI-Expanded)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 26 Sayı: 4-5
- Basım Tarihi: 2011
- Doi Numarası: 10.1155/2011/808037
- Dergi Adı: SPECTROSCOPY-BIOMEDICAL APPLICATIONS
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED)
- Sayfa Sayıları: ss.213-229
- Anahtar Kelimeler: Go alpha protein, FTIR spectroscopy, circular dichroism, homology modeling, PROTEIN SECONDARY STRUCTURE, CIRCULAR-DICHROISM, NUCLEOTIDE-BINDING, INFRARED-SPECTRA, FLUORESCENCE, MEMBRANES, SUBUNIT, HADDOCK
- Acıbadem Mehmet Ali Aydınlar Üniversitesi Adresli: Evet
Özet
Go, a member of heterotrimeric guanine nucleotide-binding proteins, is the most abundant form of G protein in the central and peripheral nervous systems. Go alpha has a significant role in neuronal development and function but its signal transduction mechanism remains to be clarified.