Evaluation of salivary and serum methylated arginine metabolites and nitric oxide synthase in advanced periodontitis patients

Sengul V., GÜNEY Z., KURGAN Ş., ÖNDER C., SERDAR M. A., GÜNHAN M.

CLINICAL ORAL INVESTIGATIONS, cilt.26, sa.7, ss.5061-5070, 2022 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 26 Sayı: 7
  • Basım Tarihi: 2022
  • Doi Numarası: 10.1007/s00784-022-04479-w
  • Dergi Adı: CLINICAL ORAL INVESTIGATIONS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, EMBASE, MEDLINE
  • Sayfa Sayıları: ss.5061-5070
  • Anahtar Kelimeler: Asymmetric dimethylarginine (ADMA), Periodontitis, Nitric oxide synthase (NOS), ASYMMETRIC DIMETHYLARGININE ADMA, ENDOTHELIAL DYSFUNCTION, OXIDATIVE STRESS, ENDOGENOUS METHYLARGININES, CARDIOVASCULAR-DISEASES, NO, INHIBITOR, SMOKING, RELEASE, COMPLEX
  • Acıbadem Mehmet Ali Aydınlar Üniversitesi Adresli: Evet

Özet

Objectives Methylated arginine metabolites and nitric oxide synthase (NOS) play a critical role in regulating endothelial function. The aim of this study was to determine levels of NOS, and methylated arginine metabolites (ADMA, SDMA, homoarginine, arginine, and L-NMMA) and IL-6 in serum and saliva in patients with advanced periodontal diseases and identify their association with clinical parameters.