Pigment Epithelium-Derived Factor Associates With Neuropathy and Fibrosis in Pancreatic Cancer

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Samkharadze T., Erkan M., Reiser-Erkan C., Demir I. E., Kong B., Ceyhan G., ...More

AMERICAN JOURNAL OF GASTROENTEROLOGY, vol.106, no.5, pp.968-980, 2011 (SCI-Expanded)

• Publication Type: Article / Article
• Volume: 106 Issue: 5
• Publication Date: 2011
• Doi Number: 10.1038/ajg.2010.479
• Journal Name: AMERICAN JOURNAL OF GASTROENTEROLOGY
• Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED)
• Page Numbers: pp.968-980
• Acibadem Mehmet Ali Aydinlar University Affiliated: No

Abstract

OBJECTIVES: Pigment epithelium-derived factor (PEDF) is a noninhibitory member of the serine protease inhibitor gene family with neuroprotective, neuroproliferative, and anti-angiogenic functions. Its role in pancreatic fibrosis and neuropathy is unknown.