Gamma knife radiosurgery for pituitary spindle cell oncocytomas

Akyoldas G., Hergunsel O. B., Ozdemir I. E., Sengoz M., Peker S.

CLINICAL NEUROLOGY AND NEUROSURGERY, vol.187, 2019 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 187
  • Publication Date: 2019
  • Doi Number: 10.1016/j.clineuro.2019.105560
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Keywords: Spindle cell, Oncocytomas, Sellar, Mass, Pituitary, Transsphenoidal, Revision, Stereotactic radiosurgery, Gamma knife, Oncology, ENDOSCOPIC ENDONASAL SURGERY, REPEAT TRANSSPHENOIDAL SURGERY, ADENOHYPOPHYSIS REPORT, RECURRENT, ADENOMAS, EXPERIENCE, TUMORS
  • Acibadem Mehmet Ali Aydinlar University Affiliated: Yes


Objectives: Spindle cell oncocytomas (SCOs) are benign lesions of the posterior portion of the pituitary gland that typically come to neurosurgical attention due to compression of the sellar or parasellar structures, and headaches. Initial treatment options for SCOs include surgical resection, particularly via the transsphenoidal approach. However, given that initial resection tends to be insufficient and subsequent revision surgery carries high complication risk, adjuvant treatment modalities may appear to offer promising solutions for controlling tumor progression. This report focuses on a potential new therapeutic option for SCOs, gamma knife radiosurgery (GKRS).