Effect of Proton Pump Inhibitor (PPI) Treatment in Obstructive Sleep Apnea Syndrome: An Esophageal Impedance-pHmetry Study

Ermis F., Akyuz F., Arici S., Uyanikoglu A., Yakar F., Pinarbasi B., ...More

HEPATO-GASTROENTEROLOGY, vol.58, no.110, pp.1566-1573, 2011 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 58 Issue: 110
  • Publication Date: 2011
  • Doi Number: 10.5754/hge10465
  • Journal Name: HEPATO-GASTROENTEROLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1566-1573
  • Keywords: GERD, Obstructive sleep apnea, Impedance-Phmetry, Acid suppressive therapy, GASTROESOPHAGEAL-REFLUX DISEASE, POSITIVE AIRWAY PRESSURE, BREATHING DISORDERS, ENDOSCOPIC FINDINGS, PH, PATHOGENESIS, ASSOCIATION, INFANTS
  • Acibadem Mehmet Ali Aydinlar University Affiliated: Yes

Abstract

Background/Aims: There is an increasing interest for a link between gastroesophageal reflux (GER) and obstructive sleep apnea syndrome (OSAS). There is no study in the literature which examines the relationship between OSAS and esophageal functions in adults with impedance. We first evaluated the role of reflux in OSAS with simultaneous polysomnography and impedance-pHmetry and then investigated whether the effect of proton pump inhibitor (PPI) treatment changes in these parameters.