COX-2 and survivin are overexpressed and positively correlated in endometrial carcinoma

Erkanli S., Bolat F., Kayaselcuk F., Demirhan B., Kuscu E.

GYNECOLOGIC ONCOLOGY, cilt.104, sa.2, ss.320-325, 2007 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 104 Sayı: 2
  • Basım Tarihi: 2007
  • Doi Numarası: 10.1016/j.ygyno.2006.08.044
  • Dergi Adı: GYNECOLOGIC ONCOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.320-325
  • Anahtar Kelimeler: COX-2, survivin, endometrial carcinoma, CYCLOOXYGENASE-2 EXPRESSION, MESSENGER-RNA, TISSUE MICROARRAY, EPITHELIAL-CELLS, GROWTH-FACTOR, CANCER, APOPTOSIS, PROTEIN, PTEN, RECEPTORS
  • Acıbadem Mehmet Ali Aydınlar Üniversitesi Adresli: Hayır

Özet

Objectives. To investigate the expressions of survivin and Cyclooxygenase-2 (COX-2), and their possible correlations in the development of endometrial adenocarcinoma (EC). We also looked at their association with classical prognostic factors in EC. To our knowledge, this is the first time survivin expression is investigated in terms Of its relation to COX-2 in the developmental pathway of EC.