Combination therapy with intrapleural doxycycline and talc in reduced doses is effective in producing pleurodesis in rabbits

Dikensoy Ö., Zhu Z., Donnelly E., Stathopoulos G., Lane K., Light R.

CHEST, cilt.128, sa.5, ss.3735-3742, 2005 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 128 Sayı: 5
  • Basım Tarihi: 2005
  • Doi Numarası: 10.1378/chest.128.5.3735
  • Dergi Adı: CHEST
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.3735-3742
  • Anahtar Kelimeler: combination, doxcycline, pleural effusion, talc, ultrasound, MALIGNANT PLEURAL EFFUSIONS, SPONTANEOUS PNEUMOTHORAX, TETRACYCLINE, BLEOMYCIN, CORTICOSTEROIDS, DIAGNOSIS, INSTILLATION, MINOCYCLINE, ULTRASOUND, MANAGEMENT
  • Acıbadem Mehmet Ali Aydınlar Üniversitesi Adresli: Hayır

Özet

Background: It has been suggested that talc and doxycycline might be acting through different pathways in creating pleurodesis. We hypothesized that combining doxycycline and talc in half the usual doses would be synergistic in inducing pleurodesis.