Combination therapy with intrapleural doxycycline and talc in reduced doses is effective in producing pleurodesis in rabbits

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Dikensoy Ö. , Zhu Z., Donnelly E., Stathopoulos G., Lane K., Light R.

CHEST, cilt.128, sa.5, ss.3735-3742, 2005 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 128 Konu: 5
  • Basım Tarihi: 2005
  • Doi Numarası: 10.1378/chest.128.5.3735
  • Dergi Adı: CHEST
  • Sayfa Sayıları: ss.3735-3742


Background: It has been suggested that talc and doxycycline might be acting through different pathways in creating pleurodesis. We hypothesized that combining doxycycline and talc in half the usual doses would be synergistic in inducing pleurodesis.