Combination therapy with intrapleural doxycycline and talc in reduced doses is effective in producing pleurodesis in rabbits

Dikensoy, ÖNER; Zhu, ZW; Donnelly, E; Stathopoulos, GT; Lane, KB; Light, RW

doi:10.1378/chest.128.5.3735

Combination therapy with intrapleural doxycycline and talc in reduced doses is effective in producing pleurodesis in rabbits

Dikensoy Ö., Zhu Z., Donnelly E., Stathopoulos G., Lane K., Light R.

CHEST, cilt.128, sa.5, ss.3735-3742, 2005 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 128 Sayı: 5
Basım Tarihi: 2005
Doi Numarası: 10.1378/chest.128.5.3735
Dergi Adı: CHEST
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.3735-3742
Anahtar Kelimeler: combination, doxcycline, pleural effusion, talc, ultrasound, MALIGNANT PLEURAL EFFUSIONS, SPONTANEOUS PNEUMOTHORAX, TETRACYCLINE, BLEOMYCIN, CORTICOSTEROIDS, DIAGNOSIS, INSTILLATION, MINOCYCLINE, ULTRASOUND, MANAGEMENT
Acıbadem Mehmet Ali Aydınlar Üniversitesi Adresli: Hayır

Özet

Background: It has been suggested that talc and doxycycline might be acting through different pathways in creating pleurodesis. We hypothesized that combining doxycycline and talc in half the usual doses would be synergistic in inducing pleurodesis.