Optic disc and retinal nerve fiber layer parameters as indicators of neurodegenerative brain changes in patients with obstructive sleep apnea syndrome

Huseyinoglu N., Ekinci M., Ozben S., Buyukuysal C., Kale M. Y., Sanivar H. S.

SLEEP AND BREATHING, cilt.18, sa.1, ss.95-102, 2014 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 18 Sayı: 1
  • Basım Tarihi: 2014
  • Doi Numarası: 10.1007/s11325-013-0854-z
  • Dergi Adı: SLEEP AND BREATHING
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.95-102
  • Anahtar Kelimeler: Obstructive sleep apnea syndrome, Optic coherence tomography, Retinal nerve fiber layer, Brain atrophy, NORMAL-TENSION GLAUCOMA, COHERENCE TOMOGRAPHY, NEURONAL APOPTOSIS, MULTIPLE-SCLEROSIS, THICKNESS, NEUROPATHY, ASSOCIATION, DEFINITION, PREVALENCE, DISEASE
  • Acıbadem Mehmet Ali Aydınlar Üniversitesi Adresli: Hayır

Özet

Purpose Retina is a unique part of the central nervous system (CNS) for visualizing the processes of axonal and neuronal degeneration. Optical coherence tomography (OCT) allows direct visualization and measurement of retinal nerve fiber layer (RNFL) thickness, macular volume, and optic disc (OD) parameters. One of the disorders associated with atrophy in different brain regions is obstructive sleep apnea syndrome (OSAS). In the present study, we aimed to determine OD and RNFL changes measured by OCT for investigating the progress of neurodegeneration development in OSAS, excluding all the other conditions that can directly affect RNFL thickness and optic nerve parameters.