Predicting Value of Serum Procalcitonin, C-Reactive Protein, Drain Fluid Culture, Drain Fluid Interleukin-6, and Tumor Necrosis Factor-α Levels in Anastomotic Leakage after Rectal Resection.

Bilgin İ. A. , Hatipoglu E., Aghayeva A. , Arikan A. E. , Incir S., TORUN M., ...More

Surgical infections, vol.18, no.3, pp.350-356, 2017 (Journal Indexed in SCI Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 18 Issue: 3
  • Publication Date: 2017
  • Doi Number: 10.1089/sur.2016.222
  • Title of Journal : Surgical infections
  • Page Numbers: pp.350-356
  • Keywords: C-reactive protein, drain fluid culture, interleukin-6, procalcitonin, rectal anastomotic leakage, tumor necrosis factor-alpha, COLORECTAL SURGERY, INTRAPERITONEAL MICRODIALYSIS, POSTOPERATIVE COMPLICATIONS, INFLAMMATORY RESPONSE, ANTERIOR RESECTION, MAJOR SURGERY, EARLY MARKERS, CANCER, CYTOKINES, SEPSIS


Background: Anastomotic leak is the most dreaded septic complication of colorectal surgical procedures. Death is proportional to the time between occurrence and diagnosis of the leakage. Biomarkers, which may help to predict anastomotic leakage before appearance of its clinical features, may be beneficial in preventing adverse outcomes. This study investigates a biomarker that might be useful to predict rectal anastomotic leakage before its clinical presentation.