INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY, vol.100, pp.132-136, 2017 (Journal Indexed in SCI)
Article / Article
Title of Journal :
INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY
Objective: Methotrexate is a dihydrofolate reductase enzyme inhibitor with very high selectivity, and it is an antiproliferative folic acid antagonist used for the treatment of autoimmune diseases. In this study, our objective was to evaluate the effect of intratympanic Methotrexate application in the inner ear.