Multiple sequence alignment based on structural properties

Creative Commons License

Ozer B., Gezici G., Meydan C., Sezerman U.

2010 5th International Symposium on Health Informatics and Bioinformatics, HIBIT 2010, Antalya, Türkiye, 20 - 22 Nisan 2010, ss.39-44 identifier

  • Yayın Türü: Bildiri / Tam Metin Bildiri
  • Doi Numarası: 10.1109/hibit.2010.5478910
  • Basıldığı Şehir: Antalya
  • Basıldığı Ülke: Türkiye
  • Sayfa Sayıları: ss.39-44
  • Anahtar Kelimeler: Cluster, Graph properties, MSA, Multiple sequence alignment
  • Acıbadem Mehmet Ali Aydınlar Üniversitesi Adresli: Hayır

Özet

A multiple sequence alignment (MSA) is a sequence alignment of three or more biological sequences. Main idea behind multiple sequence alignment is to see the similarities between input sequences, to be able to make phylogenetic analysis and other evolutionary conclusions. We propose a multiple sequence alignment method based on contact maps derived from structural data and network properties. We show that such methods may be useful in creating multiple alignments that can identify domains and similar structures where sequence identity is low. ©2009 IEEE.