INCREASED MATERNAL LEPTIN LEVELS MAY BE AN INDICATOR OF SUBCLINICAL HYPOTHYROIDISM IN A NEWBORN


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KARPUZOGLU H. , UÇAL Y. , Kumru P., Muhcu M., Eroglu M., Serdar M., ...More

JOURNAL OF MEDICAL BIOCHEMISTRY, vol.41, no.2, pp.156-161, 2022 (Journal Indexed in SCI) identifier

  • Publication Type: Article / Article
  • Volume: 41 Issue: 2
  • Publication Date: 2022
  • Doi Number: 10.5937/jomb0-32425
  • Title of Journal : JOURNAL OF MEDICAL BIOCHEMISTRY
  • Page Numbers: pp.156-161
  • Keywords: leptin, congenital hypothyroidism, maternal-fetal relations, newborn TSH (Thyroid Stimulating Hormone), maternal thyroid hormones, BODY-MASS INDEX, WEIGHT-GAIN, CORD BLOOD, PREGNANCY, OBESITY, INSULIN, FETAL, SERUM, ADIPONECTIN

Abstract

Background: Several factors may influence newborn thyroid-stimulating hormone (TSH) concentrations and cause subclinical hypothyroidism in a newborn. A sufficient level of leptin signalling is needed for the normal production of TSH and thyroid hormones by the thyroid gland. Our study aimed to investigate the correlation between maternal serum leptin concentration during the third trimester of pregnancy and newborn screening-TSH levels.