Increased maternal leptin levels may be an indicator of subclinical hypothyroidism in a newborn.

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KARPUZOGLU H., UÇAL Y., Kumru P., Muhcu M., Eroglu M., Serdar M. A., ...Daha Fazla

Journal of medical biochemistry, cilt.41, sa.2, ss.156-161, 2022 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 41 Sayı: 2
  • Basım Tarihi: 2022
  • Doi Numarası: 10.5937/jomb0-32425
  • Dergi Adı: Journal of medical biochemistry
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CAB Abstracts, Central & Eastern European Academic Source (CEEAS), EMBASE, Veterinary Science Database, Directory of Open Access Journals
  • Sayfa Sayıları: ss.156-161
  • Anahtar Kelimeler: leptin, congenital hypothyroidism, maternal-fetal relations, newborn TSH (Thyroid Stimulating Hormone), maternal thyroid hormones, BODY-MASS INDEX, WEIGHT-GAIN, CORD BLOOD, PREGNANCY, OBESITY, INSULIN, FETAL, SERUM, ADIPONECTIN
  • Acıbadem Mehmet Ali Aydınlar Üniversitesi Adresli: Evet

Özet

Background: Several factors may influence newborn thyroid-stimulating hormone (TSH) concentrations and cause subclinical hypothyroidism in a newborn. A sufficient level of leptin signalling is needed for the normal production of TSH and thyroid hormones by the thyroid gland. Our study aimed to investigate the correlation between maternal serum leptin concentration during the third trimester of pregnancy and newborn screening-TSH levels.