Increased maternal leptin levels may be an indicator of subclinical hypothyroidism in a newborn.

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KARPUZOGLU H., UÇAL Y., Kumru P., Muhcu M., Eroglu M., Serdar M. A., ...More

Journal of medical biochemistry, vol.41, no.2, pp.156-161, 2022 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 41 Issue: 2
  • Publication Date: 2022
  • Doi Number: 10.5937/jomb0-32425
  • Journal Name: Journal of medical biochemistry
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CAB Abstracts, Central & Eastern European Academic Source (CEEAS), EMBASE, Veterinary Science Database, Directory of Open Access Journals
  • Page Numbers: pp.156-161
  • Keywords: leptin, congenital hypothyroidism, maternal-fetal relations, newborn TSH (Thyroid Stimulating Hormone), maternal thyroid hormones, BODY-MASS INDEX, WEIGHT-GAIN, CORD BLOOD, PREGNANCY, OBESITY, INSULIN, FETAL, SERUM, ADIPONECTIN
  • Acibadem Mehmet Ali Aydinlar University Affiliated: Yes


Background: Several factors may influence newborn thyroid-stimulating hormone (TSH) concentrations and cause subclinical hypothyroidism in a newborn. A sufficient level of leptin signalling is needed for the normal production of TSH and thyroid hormones by the thyroid gland. Our study aimed to investigate the correlation between maternal serum leptin concentration during the third trimester of pregnancy and newborn screening-TSH levels.