Copy For Citation
Ekenel M., Avsar E., Imeryuz N., Yuksel M., Haklar G., Kocakaya O., ...More
EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY, vol.15, no.4, pp.403-406, 2003 (SCI-Expanded)
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Publication Type:
Article / Article
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Volume:
15
Issue:
4
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Publication Date:
2003
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Doi Number:
10.1097/00042737-200304000-00011
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Journal Name:
EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY
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Journal Indexes:
Science Citation Index Expanded (SCI-EXPANDED), Scopus
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Page Numbers:
pp.403-406
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Keywords:
COX-2 inhibitors, gastric damage, sucrose permeability, RANDOMIZED CONTROLLED TRIAL, RHEUMATOID-ARTHRITIS, DOUBLE-BLIND, CYCLOOXYGENASE-2 INHIBITORS, GASTROINTESTINAL TOXICITY, OSTEOARTHRITIS, ROFECOXIB, CELECOXIB, EFFICACY, TOLERABILITY
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Acibadem Mehmet Ali Aydinlar University Affiliated:
No
Abstract
Objective Acute and chronic use of non-steroidal anti-inflammatory drugs can increase gastrointestinal permeability. Celecoxib, which selectively inhibits the enzyme cyclooxygenase-2, is a novel anti-inflammatory drug with minimal gastrointestinal toxic effects while retaining anti-inflammatory efficacy. Our aim was to assess the potential effects of celecoxib on gastric permeability in comparison with placebo and ibuprofen.