Türk Anesteziyoloji ve Reanimasyon Derneği 55. Ulusal Kongresi-TARK 2021, Antalya, Türkiye, 28 - 31 Ekim 2021, ss.798-799
Abstract
Background and Aim of the Study: Transfusion‐associated hyperpotassemia is a serious
complication of packed red blood cell (PRBC) transfusion after congenital cardiac surgery.
Our study aimed to identify risk factors and potential preventive measures of transfusion‐
associated hyperpotassemia in neonates and infants after congenital cardiac surgery.
Methods: Pediatric patients who underwent congenital cardiac surgery and need
transfusion were enrolled in this prospective study. The potassium concentration of PRBC
was checked from the sample taken from the segment. The volume of transfusion, age of
PRBC, and potassium concentration of unit were recorded. The estimated increment of potassium level in patients after PRBC transfusion was calculated.
Results: Seventy‐four individual patients, 95 distinct transfusions, and 112 blood products were evaluated. The mean age of the blood unit was 3.8 ± 1.4 days. The mean
potassium concentration in the PRBCs was 9.9 ± 2.4 mmol/L. A weak correlation was
observed between the potassium value of the PRBC and the age of PRBC (p = 0.049,
r = 0.2, y = 0.24 × x + −0.68). There was a weak correlation between the potassium
value of PRBCs and the age of the unit (p < 0.001, r = 0.37, y = 2.8 × x + −3.6).
Conclusions: Before transfusion, even PRBC is fresh, measuring the potassium level
of PRBC and the potassium that will be given to the pediatric patient with transfusion can prevent transfusion‐related hyperpotassemia and related complications.
Otherwise, high potassium levels, which may be overlooked despite being fresh, may
cause serious complications, even cardiac arrest, especially in neonates and infants.
KEYWORDS
congenital cardiac surgery, infant, neonatal, packed red blood cell transfusion, segment
potassium concentration