Paraneoplastic acrokeratosis of Bazex (Bazex's syndrome): Report of a female case associated with cholangiocarcinoma and review of the published work

Karabulut A. A., Sahin S., Sahin M., Eksioglu M., Ustun H.

JOURNAL OF DERMATOLOGY, vol.33, no.12, pp.850-854, 2006 (SCI-Expanded, Scopus) identifier identifier identifier identifier

  • Publication Type: Article / Review
  • Volume: 33 Issue: 12
  • Publication Date: 2006
  • Doi Number: 10.1111/j.1346-8138.2006.00194.x
  • Journal Name: JOURNAL OF DERMATOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.850-854
  • Keywords: cholangiocarcinoma, paraneoplastic acrokeratosis of Bazex, paraneoplastic dermatosis, PARA-NEOPLASTIC ACROKERATOSIS, SQUAMOUS-CELL CARCINOMA, ADENOCARCINOMA, PATIENT, WOMAN
  • Acibadem Mehmet Ali Aydinlar University Affiliated: No

Abstract

Paraneoplastic acrokeratosis of Bazex (PAB) or Bazex's syndrome is a rare, paraneoplastic syndrome that mostly affects men over 40 years old, and generally associates with squamous cell carcinoma of the upper aerodigestive tract. We describe a 57-year-old woman with the characteristic features of PAB, including violaceous erythematous, scaling eruption, palmoplantar keratoderma and nail dystrophy. Further analysis revealed the underlying neoplasm to be cholangiocarcinoma. The clinical aspects of PAB and associated neoplasms are reviewed.