Dietary supplementation with low-dose omega-3 fatty acids reduces salivary tumor necrosis factor-alpha levels in patients with chronic periodontitis: a randomized controlled clinical study


Keskiner I., Saygun I., Bal V., Serdar M. A., Kantarci A.

JOURNAL OF PERIODONTAL RESEARCH, vol.52, no.4, pp.695-703, 2017 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 52 Issue: 4
  • Publication Date: 2017
  • Doi Number: 10.1111/jre.12434
  • Journal Name: JOURNAL OF PERIODONTAL RESEARCH
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.695-703
  • Keywords: chronic periodontitis, omega-3, saliva, tumor necrosis factor-alpha, POLYUNSATURATED FATTY-ACIDS, GINGIVAL CREVICULAR FLUID, FISH-OIL SUPPLEMENTATION, HOST RESPONSE MODULATION, SUPEROXIDE-DISMUTASE, LIPID-PEROXIDATION, DOCOSAHEXAENOIC ACIDS, ANTIOXIDANT ENZYMES, MONONUCLEAR-CELLS, IMMUNE FUNCTION
  • Acibadem Mehmet Ali Aydinlar University Affiliated: Yes

Abstract

Background and Objective: Recent studies have demonstrated the beneficial effects of omega-3 polyunsaturated fatty acids (PUFAs) on physiological processes and on a variety of chronic inflammatory diseases, including periodontal diseases. In this study, we evaluated the impact of omega-3 PUFAs in conjunction with scaling and root planing (SRP) on salivary markers in patients with chronic periodontitis.