Dietary supplementation with low-dose omega-3 fatty acids reduces salivary tumor necrosis factor-alpha levels in patients with chronic periodontitis: a randomized controlled clinical study

Keskiner I., Saygun I., Bal V., Serdar M. A., Kantarci A.

JOURNAL OF PERIODONTAL RESEARCH, cilt.52, sa.4, ss.695-703, 2017 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 52 Sayı: 4
  • Basım Tarihi: 2017
  • Doi Numarası: 10.1111/jre.12434
  • Dergi Adı: JOURNAL OF PERIODONTAL RESEARCH
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.695-703
  • Anahtar Kelimeler: chronic periodontitis, omega-3, saliva, tumor necrosis factor-alpha, POLYUNSATURATED FATTY-ACIDS, GINGIVAL CREVICULAR FLUID, FISH-OIL SUPPLEMENTATION, HOST RESPONSE MODULATION, SUPEROXIDE-DISMUTASE, LIPID-PEROXIDATION, DOCOSAHEXAENOIC ACIDS, ANTIOXIDANT ENZYMES, MONONUCLEAR-CELLS, IMMUNE FUNCTION
  • Acıbadem Mehmet Ali Aydınlar Üniversitesi Adresli: Evet

Özet

Background and Objective: Recent studies have demonstrated the beneficial effects of omega-3 polyunsaturated fatty acids (PUFAs) on physiological processes and on a variety of chronic inflammatory diseases, including periodontal diseases. In this study, we evaluated the impact of omega-3 PUFAs in conjunction with scaling and root planing (SRP) on salivary markers in patients with chronic periodontitis.