AMERICAN JOURNAL OF RHINOLOGY, vol.22, no.3, pp.219-222, 2008 (SCI-Expanded)
Background: Pregnancy-associated plasma protein A (PAPP-A), also known as insulin-like growth factor binding protein 4 protease, is postulated to be a new inflammatory marker in various clinical situations such as cardiovascular events, dialysis, renal transplantation, and asthma. PAPP-A also is produced in high concentrations by trophoblasts during pregnancy.