Localisation analysis of nerves in the mouse pancreas reveals the sites of highest nerve density and nociceptive innervation


Saricaoglu O. C. , Teller S., Wang X., Wang S., Stupakov P., Heinrich T., ...Daha Fazla

NEUROGASTROENTEROLOGY AND MOTILITY, 2020 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası:
  • Basım Tarihi: 2020
  • Doi Numarası: 10.1111/nmo.13880
  • Dergi Adı: NEUROGASTROENTEROLOGY AND MOTILITY

Özet

Background Neuropathy and neuro-inflammation drive the severe pain and disease progression in human chronic pancreatitis and pancreatic cancer. Mice, especially genetically induced-mouse models, have been increasingly utilized in mechanistic research on pancreatic neuropathy, but the normal "peripheral neurobiology" of the mouse pancreas has not yet been critically compared to human pancreas.