Morbilliform drug eruption due to pegylated alpha-interferon can show complete regression after switching to non-pegylated interferon

Barut S., Yuksek J., Sezer E., Gunal O., Koseoglu D.

JOURNAL OF DERMATOLOGY, vol.38, no.5, pp.479-481, 2011 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 38 Issue: 5
  • Publication Date: 2011
  • Doi Number: 10.1111/j.1346-8138.2010.01088.x
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED)
  • Page Numbers: pp.479-481
  • Acibadem Mehmet Ali Aydinlar University Affiliated: Yes


Pegylated or non-pegylated alpha-interferon are frequently used medications for the treatment of both chronic hepatitis B and chronic hepatitis C. Skin disorders, which are mainly comprised of eczematous dermatitis, are frequently seen during treatment with this drug. However, drug eruption or morbilliform eruptions due to interferons have been rarely reported so far. We herein describe a patient who developed morbilliform drug eruption under treatment with pegylated interferon. She was able to continue treatment after switching from pegylated interferon to conventional interferon.