Effect of nitrogen mustard, a vesicant agent, on lymphocyte energy metabolism

Kenar L., Boyunaga H., Serdar M. A., Karayilanoglu T., Erbil M. K.

CLINICAL CHEMISTRY AND LABORATORY MEDICINE, cilt.44, sa.10, ss.1253-1257, 2006 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 44 Sayı: 10
  • Basım Tarihi: 2006
  • Doi Numarası: 10.1515/cclm.2006.220
  • Dergi Adı: CLINICAL CHEMISTRY AND LABORATORY MEDICINE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1253-1257
  • Anahtar Kelimeler: energy metabolism, glycogen degradation, glycolysis, mechlorethamine, mustard, BUTYL 2-CHLOROETHYL SULFIDE, SULFUR MUSTARD, SUBCUTANEOUS INJECTION, WARFARE AGENT, GENERATION, MECHANISM, APOPTOSIS, MIRACIDIA, GLUCOSE
  • Acıbadem Mehmet Ali Aydınlar Üniversitesi Adresli: Hayır

Özet

Background: The vesicant agents sulfur and nitrogen mustards, which contain chloroethyl groups, are potent inhibitors of DNA synthesis and cell growth, likely changing the utilization of anaerobic glycolysis for energy generation.