Proteomic profiling of HBV infected liver biopsies with different fibrotic stages


Katrinli Ş., Ozdil K., Sahin A., Ozturk O., Kir G., Baykal A. T. , ...More

PROTEOME SCIENCE, vol.15, 2017 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 15
  • Publication Date: 2017
  • Doi Number: 10.1186/s12953-017-0114-4
  • Journal Name: PROTEOME SCIENCE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED)
  • Keywords: Liver fibrosis, Chronic hepatitis B, Two-dimensional difference gel electrophoresis, Proteomics, Glycolysis, HEPATITIS-B-VIRUS, HEPATOCELLULAR-CARCINOMA, X PROTEIN, FIBROSIS, EXPRESSION, METABOLISM, BIOMARKERS, ASSOCIATION, KINASE
  • Acibadem Mehmet Ali Aydinlar University Affiliated: Yes

Abstract

Background: Hepatitis B virus (HBV) is a global health problem, and infected patients if left untreated may develop cirrhosis and eventually hepatocellular carcinoma. This study aims to enlighten pathways associated with HBV related liver fibrosis for delineation of potential new therapeutic targets and biomarkers.