Proteomic profiling of HBV infected liver biopsies with different fibrotic stages

Katrinli Ş., Ozdil K., Sahin A., Ozturk O., Kir G., Baykal A. T., ...Daha Fazla

PROTEOME SCIENCE, cilt.15, 2017 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 15
  • Basım Tarihi: 2017
  • Doi Numarası: 10.1186/s12953-017-0114-4
  • Dergi Adı: PROTEOME SCIENCE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Anahtar Kelimeler: Liver fibrosis, Chronic hepatitis B, Two-dimensional difference gel electrophoresis, Proteomics, Glycolysis, HEPATITIS-B-VIRUS, HEPATOCELLULAR-CARCINOMA, X PROTEIN, FIBROSIS, EXPRESSION, METABOLISM, BIOMARKERS, ASSOCIATION, KINASE
  • Acıbadem Mehmet Ali Aydınlar Üniversitesi Adresli: Evet

Özet

Background: Hepatitis B virus (HBV) is a global health problem, and infected patients if left untreated may develop cirrhosis and eventually hepatocellular carcinoma. This study aims to enlighten pathways associated with HBV related liver fibrosis for delineation of potential new therapeutic targets and biomarkers.