Monoglycoconjugated phthalocyanines: Effect of sugar and linkage on photodynamic activity

Lafont D., Zorlu Y., Savoie H., Albrieux F., Ahsen V., Boyle R. W., ...Daha Fazla

PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY, cilt.10, sa.3, ss.252-259, 2013 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 10 Sayı: 3
  • Basım Tarihi: 2013
  • Doi Numarası: 10.1016/j.pdpdt.2012.11.009
  • Dergi Adı: PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.252-259
  • Anahtar Kelimeler: Photodynamic therapy, Photosensitiser, Phthalocyanine, Carbohydrate, Click chemistry, GLYCOCONJUGATED PORPHYRINS, CLICK-CHEMISTRY, THERAPY, PHOTOSENSITIZERS, DERIVATIVES, GLYCEROL
  • Acıbadem Mehmet Ali Aydınlar Üniversitesi Adresli: Hayır

Özet

Background: Click chemistry can be advantageously used to graft carbohydrates on phthalocyanines which are potent photosensitisers, but the effect of the presence of triazole moieties on photodynamic efficiency was not investigated systematically to date. The nature and linkage of the sugar were investigated in order to define structure activity relationships.