Effect of magnesium supplementation and depletion on the onset and course of acute experimental pancreatitis

Schick V., Scheiber J. A., Mooren F. C., Turi S., Ceyhan G., Schnekenburger J., ...More

GUT, vol.63, no.9, pp.1469-1480, 2014 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 63 Issue: 9
  • Publication Date: 2014
  • Doi Number: 10.1136/gutjnl-2012-304274
  • Journal Name: GUT
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1469-1480
  • Acibadem Mehmet Ali Aydinlar University Affiliated: No


Background and objective High calcium concentrations are an established risk factor for pancreatitis. We have investigated whether increasing magnesium concentrations affect pathological calcium signals and premature protease activation in pancreatic acini, and whether dietary or intraperitoneal magnesium administration affects the onset and course of experimental pancreatitis.