Effect of magnesium supplementation and depletion on the onset and course of acute experimental pancreatitis


Schick V., Scheiber J. A. , Mooren F. C. , Turi S., Ceyhan G. , Schnekenburger J., ...More

GUT, vol.63, no.9, pp.1469-1480, 2014 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 63 Issue: 9
  • Publication Date: 2014
  • Doi Number: 10.1136/gutjnl-2012-304274
  • Title of Journal : GUT
  • Page Numbers: pp.1469-1480

Abstract

Background and objective High calcium concentrations are an established risk factor for pancreatitis. We have investigated whether increasing magnesium concentrations affect pathological calcium signals and premature protease activation in pancreatic acini, and whether dietary or intraperitoneal magnesium administration affects the onset and course of experimental pancreatitis.