Effect of magnesium supplementation and depletion on the onset and course of acute experimental pancreatitis

Schick, Verena; Scheiber, Jonas; Mooren, Frank; Turi, Stefan; Ceyhan, GÜRALP; Schnekenburger, Juergen; Sendler, Matthias; Schwaiger, Theresa; Omercevic, Armin; van den Brandt, Cindy; Fluhr, Gabriele; Domschke, Wolfram; Krueger, Burkhard; Mayerle, Julia; Lerch, Markus

doi:10.1136/gutjnl-2012-304274

Effect of magnesium supplementation and depletion on the onset and course of acute experimental pancreatitis

Schick V., Scheiber J. A., Mooren F. C., Turi S., Ceyhan G., Schnekenburger J., ...Daha Fazla

GUT, cilt.63, sa.9, ss.1469-1480, 2014 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 63 Sayı: 9
Basım Tarihi: 2014
Doi Numarası: 10.1136/gutjnl-2012-304274
Dergi Adı: GUT
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.1469-1480
Acıbadem Mehmet Ali Aydınlar Üniversitesi Adresli: Hayır

Özet

Background and objective High calcium concentrations are an established risk factor for pancreatitis. We have investigated whether increasing magnesium concentrations affect pathological calcium signals and premature protease activation in pancreatic acini, and whether dietary or intraperitoneal magnesium administration affects the onset and course of experimental pancreatitis.