Investigation of Potential Anticarcinogenic Effects of Corilagin in Lung Cancer Cells

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Rencuzogullari C., Cincin Z. B., Iplik E. S., Baran Y., ÇAKMAKOĞLU B.

CLINICAL AND EXPERIMENTAL HEALTH SCIENCES, cilt.9, sa.3, ss.228-231, 2019 (ESCI) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 9 Sayı: 3
  • Basım Tarihi: 2019
  • Doi Numarası: 10.33808/clinexphealthsci.599707
  • Dergi Adı: CLINICAL AND EXPERIMENTAL HEALTH SCIENCES
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.228-231
  • Anahtar Kelimeler: Corilagin, antiapoptotic, non-small cell lung cancer, ANTITUMOR-ACTIVITY, GROWTH, IGF-1R
  • Acıbadem Mehmet Ali Aydınlar Üniversitesi Adresli: Hayır

Özet

Objective: Lung cancer (LC) is the most extensive reason of cancer associated deaths in men and women in the world. LC categorizes into two main groups due to their molecular clinicopathological features and therapeutic responses. Non-small cell lung cancer (NSCLC) is the main subgroup that consists of nearly 85% of all lung cancer types. Corilagin, a biologically active ellagitannin, could be extracted from Phyllanthus species which are known as Chinese medicinal plant. It has been recently shown that Corilagin could exert anti-inflammatuar and antioxidative effects in different experimental cancer models. However, the molecular effects of Corilagin in NSCLC remain unclear.