Decreased oxidation susceptibility of plasma low density lipoproteins in patients with Gilbert's syndrome


Yesilova Z., Serdar M. A. , Ercin C. N. , Gunay A., Kilciler G., Hasimi A., ...More

JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, vol.23, no.10, pp.1556-1560, 2008 (Peer-Reviewed Journal) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 23 Issue: 10
  • Publication Date: 2008
  • Doi Number: 10.1111/j.1440-1746.2008.05388.x
  • Journal Name: JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
  • Journal Indexes: Science Citation Index Expanded
  • Page Numbers: pp.1556-1560
  • Keywords: bilirubin, Gilbert's syndrome, low-density lipoprotein (LDL) oxidation, CORONARY-ARTERY-DISEASE, ISCHEMIC-HEART-DISEASE, HEME OXYGENASE, SERUM BILIRUBIN, EXPRESSION, RISK, ATHEROSCLEROSIS, ASSOCIATION, REPERFUSION, ANTIOXIDANT

Abstract

Background and Aim: The association of hyperbilirubinemia in Gilbert's syndrome (GS) with a decrease in prevalence of coronary artery disease is a well-known phenomenon. In this study, the state of low-density lipoprotein (LDL) oxidation which has been postulated to be a significant determinant at the etiopathogenesis of atherosclerotic disorders was investigated among individuals with GS.