Ceftriaxone-induced haemolytic anaemia in a child with no immune deficiency or haematological disease

ÇITAK A., Garratty G., Ucsel R., Karabocuoglu M., Uzel N.

JOURNAL OF PAEDIATRICS AND CHILD HEALTH, cilt.38, sa.2, ss.209-210, 2002 (SCI-Expanded) identifier identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 38 Sayı: 2
  • Basım Tarihi: 2002
  • Doi Numarası: 10.1046/j.1440-1754.2002.00778.x
  • Dergi Adı: JOURNAL OF PAEDIATRICS AND CHILD HEALTH
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.209-210
  • Anahtar Kelimeler: ceftriaxone, haemolysis, immune complex, steroid, SICKLE-CELL-ANEMIA, HEMOLYTIC-ANEMIA, FATAL HEMOLYSIS
  • Acıbadem Mehmet Ali Aydınlar Üniversitesi Adresli: Hayır

Özet

A 5-year-old girl, with no underlying immune deficiency or haematologic disease, was treated with ceftriaxone for a urinary tract infection. After receiving ceftriaxone intramuscularly, massive haemolytic anaemia developed. Laboratory studies showed the presence of an antibody against ceftriaxone, and the findings reflected immune complex type haemolysis. High-dose corticosteroids appeared to be effective therapeutically.