Treatment of High-grade Non-muscle-invasive Bladder Carcinoma by Standard Number and Dose of BCG Instillations Versus Reduced Number and Standard Dose of BCG Instillations: Results of the European Association of Urology Research Foundation Randomised Phase III Clinical Trial

Grimm, Marc-Oliver; van der Heijden, Antoine; Colombel, Marc; Muilwijk, Tim; Martinez-Pineiro, Luis; Babjuk, Marko; Turkeri, LEVENT; Palou, Joan; Patel, Anup; Bjartell, Anders; Caris, Christien; Schipper, Raymond; Witjes, Wim; Horstmann, Joerg; Machtens, Stefan; Mumperow, Eberhard; Al Ghazal, Andreas; Pulte, Thomas; Stephan-Odenthal, Michael; Gakis, Georgios; Kramer, Mario; Zaak, Dirk; Schmitz-Draeger, Bernd; Schreier, Holger; Lehmann, Jan; Werner, Torsten; Klier, Joerg; Marin, Jan; Rulf, Wolfgang; Hellmis, Eva; Schneider, Andreas; Spiegelhalder, Spiegelhalder; Wirth, Manfred; Klotz, Theodor; Suttmann, Henrik; Siebels, Michael; Rodemer, Gerd; Rudolph, Robert; Zillmann, Roger; de Bruin, M.; Bos, S.; van Moorselaar, R.; de Reijke, T.; Boormans, J.; Wijsman, B.; van Melick, H.; van Boven, E.; Meijer, R.; van der Heijden, A.; Vergunst, H.; te Slaa, E.; Leliveld-Kors, A.; Ruffion, Alain; Pfister, Christian; Roupret, Morgan; Irani, Jacques; Stoica, Gabriel; Van Bruwaene, Siska; Ameye, Filip; Arentsen, Harm; Joniau, Steven; Beardo, Pastora

doi:10.1016/j.eururo.2020.04.066

Treatment of High-grade Non-muscle-invasive Bladder Carcinoma by Standard Number and Dose of BCG Instillations Versus Reduced Number and Standard Dose of BCG Instillations: Results of the European Association of Urology Research Foundation Randomised Phase III Clinical Trial "NIMBUS".

Grimm M., van der Heijden A. G., Colombel M., Muilwijk T., Martinez-Pineiro L., Babjuk M. M., ...Daha Fazla

European urology, cilt.78, sa.5, ss.690-698, 2020 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 78 Sayı: 5
Basım Tarihi: 2020
Doi Numarası: 10.1016/j.eururo.2020.04.066
Dergi Adı: European urology
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, PASCAL, BIOSIS, EMBASE, Gender Studies Database, MEDLINE
Sayfa Sayıları: ss.690-698
Anahtar Kelimeler: Bacillus Calmette-Guerin, Instillation therapy, Non-muscle-invasive bladder cancer, Reduced frequency, BACILLUS-CALMETTE-GUERIN, MITOMYCIN-C, TRANSURETHRAL RESECTION, FORMAL METAANALYSIS, CELL CARCINOMA, CANCER, RISK, PROGRESSION, T1, RECURRENCE
Acıbadem Mehmet Ali Aydınlar Üniversitesi Adresli: Evet

Özet

Background: Intravesical instillation of bacillus Calmette-Guerin (BCG) is an accepted strategy to prevent recurrence of non-muscle-invasive bladder cancer (NMIBC) but associated with significant toxicity.