Patient-Reported Tolerance of Magnetic Resonance-Guided Radiation Therapy.


Sayan M., Serbez I., Teymur B., Gur G., Zoto Mustafayev T., Gungor G. , ...More

Frontiers in oncology, vol.10, pp.1782, 2020 (Journal Indexed in SCI Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 10
  • Publication Date: 2020
  • Doi Number: 10.3389/fonc.2020.01782
  • Title of Journal : Frontiers in oncology
  • Page Numbers: pp.1782
  • Keywords: MR-guided, MR-linac, patient tolerance, patient-reported outcomes, radiotherapy, RADIOTHERAPY

Abstract

© Copyright © 2020 Sayan, Serbez, Teymur, Gur, Zoto Mustafayev, Gungor, Atalar and Ozyar.Purpose: Magnetic resonance-guided radiation therapy (MRgRT) has been incorporated into a growing number of clinical practices world-wide, however, there is limited data on patient experiences with MRgRT. The purpose of this study was to prospectively evaluate patient tolerance of MRgRT using patient reported outcome questionnaires (PRO-Q). Methods: Ninety patients were enrolled in this prospective observational study and treated with MRgRT (MRIdian Linac System, ViewRay Inc. Oakwood Village, OH, United States) between September 2018 and September 2019. Breath-hold-gated dose delivery with audiovisual feedback was completed as needed. Patients completed an in-house developed PRO-Q after the first and last fraction of MRgRT. Results: The most commonly treated anatomic sites were the abdomen (47%) and pelvis (33%). Respiratory gating was utilized in 62% of the patients. Patients rated their experience as positive or at least tolerable with mean scores of 1.0–2.8. The most common complaint was the temperature in the room (61%) followed by paresthesias (57%). The degree of anxiety reported by 45% of the patients significantly decreased at the completion of treatment (mean score 1.54 vs. 1.36, p = 0.01). Forty-three percent of the patients reported some degree of disturbing noise which was improved considerably by use of music. All patients appreciated their active role during the treatment. Conclusion: This evaluation of PROs indicates that MRgRT was well-tolerated by our patients. Patients’ experience may further improve with adjustment of room temperature and noise reduction.