High treatment modification rates with lamivudine therapy in HBV-infected patients with low baseline viremia and early virological response: A multicenter study

GÖNEN, CAN; Gunduz, Feyza; Doganay, Levent; Enc, Feruze; Yegin, Ender; Ahishali, Emel; Erdem, Emrullah; Sokmen, Mehmet; Tuncer, Ilyas; Ozdogan, Osman

doi:10.1111/1751-2980.12237

High treatment modification rates with lamivudine therapy in HBV-infected patients with low baseline viremia and early virological response: A multicenter study

GÖNEN C., Gunduz F., Doganay L., Enc F. Y., Yegin E. G., Ahishali E., ...Daha Fazla

JOURNAL OF DIGESTIVE DISEASES, cilt.16, sa.5, ss.286-292, 2015 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 16 Sayı: 5
Basım Tarihi: 2015
Doi Numarası: 10.1111/1751-2980.12237
Dergi Adı: JOURNAL OF DIGESTIVE DISEASES
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.286-292
Anahtar Kelimeler: early response, hepatitis B virus, lamivudine, resistance, viral load, CHRONIC HEPATITIS-B, SURFACE-ANTIGEN, VIRUS-DNA, BREAKTHROUGH
Acıbadem Mehmet Ali Aydınlar Üniversitesi Adresli: Hayır

Özet

ObjectiveLow baseline viremia and an early treatment response predict the best outcomes in hepatitis B virus (HBV)-infected patients treated with nucleoside analogues with low barriers to resistance. The aim of this study was to assess the long-term results and effectiveness of lamivudine in patients with low baseline viremia and early virological treatment response.