Comparison of hyperbaric oxygen versus iloprost treatment in an experimental rat central retinal artery occlusion model

Karaman S., Ozkan B., YAZIR Y., Yardimoglu M., Gok M., Kara O., ...Daha Fazla

GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY, cilt.254, sa.11, ss.2209-2215, 2016 (SCI-Expanded) identifier identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 254 Sayı: 11
  • Basım Tarihi: 2016
  • Doi Numarası: 10.1007/s00417-016-3444-5
  • Dergi Adı: GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.2209-2215
  • Anahtar Kelimeler: Retinal artery occlusion, Hyperbaric oxygen therapy, Iloprost, Ischemia-reperfusion injury, ISCHEMIA-REPERFUSION INJURY, CRITICAL LIMB ISCHEMIA, SPINAL-CORD ISCHEMIA, IN-VIVO EVALUATION, RABBIT MODEL, HYPERTENSION, DISEASE, ANALOG
  • Acıbadem Mehmet Ali Aydınlar Üniversitesi Adresli: Hayır

Özet

Central retinal artery occlusion (CRAO) is one of the serious ophthalmological emergencies with poor visual prognosis. Iloprost is a stable prostacyclin analogue and has prominent anti-edema, anti-inflammatory, vasodilatory, and antiagregant effects. The main objective of this work was to investigate iloprost as an alternative agent versus hyperbaric oxygen (HBO) in the treatment of CRAO.