Akademik Veri Yönetim Sistemi
52nd ESCP Symposium on Clinical Pharmacy, Krakow, Polonya, 21 - 23 Ekim 2024, cilt.47, ss.534-535, (Özet Bildiri)
Background: Nausea and vomiting during pregnancy (NVP) impacts about 70% of pregnant women [1]. Since the pregnant women need to use medicine or supplement to cope with nausea and vomiting (NV), it is necessary to determine the severity of pregnancy-related NV, evaluate the results of the treatment applied, and provide patient counseling in order to guide patients correctly.
Aim: This research was aimed to determine the severity of pregnancy-related nausea and vomiting in pregnant woemen, to evaluate the effectiveness of treatments used on the severity of pregnancy-related NV, to detect the health problems experienced during pregnancy and medicines used and to identify the issues that pharmacist consultancy is needed.
Method: A pilot prospective observational study was carried out between 6 November 2023–4 March 2024 at the gynecology and obstetrics department of a private hospital. Pregnant women who complaints from pregnancy-related NV and admitted to join to the research were included. The Pregnancy-Specific Nausea and Vomiting Severity Scale (PUQE-24) and additional questions were applied via face to face. Sociodemographic data of participants, other health problems they experienced during pregnancy, medicines they used and PUQE-24 were assessed. Descriptive statistical analyzes and paired t-test were performed using the SPSS 22.0 program to analyze the data.
Results: 21 participants with a mean age of 32.5 ± 1.22 were participated. 16 (76%) participants got bachelor degree and 15 (71%) of all were working. 16 (76%) of the participants were experiencing pregnancy for the first time. 4 (80%) of the remaining had experienced NV during their previous pregnancies. 16 (76%) of all had lived health problems during pregnancy. Hyperemesis gravidarum (29%), iron deficiency (29%), vitamin D deficiency (14%) were the most commonly seen other health problems. The mean PUQE-24 score of the participants was 5.90 ± 2.54 at the baseline, after 1st intervention it was changed as 3.90 ± 2.13. Because of 7 (33%) of the participants’ symptoms not solved completely, they needed 2nd intervention. Before 2nd intervention their mean PUQE-24 score was 5.71 ± 1.85 and after 2nd intervention it was changed as 3 ± 1.16. There was a statistically significant decrease in the mean score of the participants after each intervention (p < 0.05). Ginger was the most commonly prescribed (71%) product which was followed by the doxylamine + pyridoxine (29%).
Conclusion: It was shown that even though the severity of NVP is mild, the pregnant women require to use supplement/medicine to cope with it. Considering this demand and the fact that herbal products are commonly prescribed, pharmacist consultancy is of great importance in terms of guiding the patient correctly and protecting them from misuse. In addition, pharmacists’ counselling regarding vitamin-mineral deficiencies that are common during pregnancy, and to direct the patient to a physician in case of requirement is important.
References/Acknowledgments
Heitmann K, Holst L, Lupattelli A, et al. Treatment of nausea in pregnancy: A cross-sectional multinational web-based study of pregnant women and new mothers. BMC Pregnancy and Childbirth, 2015;15:321. https://doi.org/10.1186/s12884-015-0746-2
This research was funded by TÜBİTAK 2209-A program code with the project number 1919B012330570.