The Persistent Challenges of Diagnosing Orthopaedic Implant-Related Infections

Lum Z. C., Cohen-Rosenblum A., Yao J. J., Chen A. F., Landy D. C., PARVİZİ J.

Journal of Bone and Joint Surgery, 2026 (SCI-Expanded, Scopus) identifier identifier

  • Yayın Türü: Makale / Editöre Mektup
  • Basım Tarihi: 2026
  • Doi Numarası: 10.2106/jbjs.25.01516
  • Dergi Adı: Journal of Bone and Joint Surgery
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, CINAHL, EMBASE, MEDLINE, Public Affairs Index, Nature Index
  • Acıbadem Mehmet Ali Aydınlar Üniversitesi Adresli: Evet

Özet

Infection remains one of the most catastrophic complications following orthopaedic surgery. Despite substantial advances in molecular diagnostics, biomarker assays, and consensus definitions, accurately diagnosing orthopaedic infection continues to challenge even the most experienced clinicians. There are differences in the diagnosis and treatment of infections that are related to different anatomic regions. The difficulty arises from the inherent biological diversity of infecting organisms and surgical locations, variable host responses, and the absence of a true diagnostic “gold standard.” This article summarizes the current diagnostic challenges and emerging solutions, drawing on recent high-impact evidence and consensus frameworks.