Can preconditioning reduce laparoscopy-induced tissue injury?


Yilmaz S., Koken T., Tokyol C., Kahraman A., Akbulut G., Serteser M. , ...More

SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES, vol.17, no.5, pp.819-824, 2003 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 17 Issue: 5
  • Publication Date: 2003
  • Doi Number: 10.1007/s00464-002-9096-z
  • Title of Journal : SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
  • Page Numbers: pp.819-824
  • Keywords: ischemia, laparoscopy, pneumoperitoneum, preconditioning, reperfusion, HEPATIC ISCHEMIA-REPERFUSION, OXIDATIVE STRESS MARKERS, BLOOD-FLOW, LIVER, PRESSURE, SURGERY, KIDNEY

Abstract

Background: Pneumoperitoneum (P) created to facilitate laparoscopy (L) is associated with splanchnic perfusion, ischemia/reperfusion (I/R) injury, and oxidative stress. In this randomized controlled experimental study with blind outcome assessment, we evaluated the effect of preconditioning (PRE) on L-induced I/R injury.