Time course of collagen peak in bile duct-ligated rats


Tarcin O., Basaranoglu M., Tahan V., Tahan G., Sucullu I., Yilmaz N., ...Daha Fazla

BMC GASTROENTEROLOGY, cilt.11, 2011 (SCI İndekslerine Giren Dergi) identifier identifier identifier

Özet

Background: One of the most useful experimental fibrogenesis models is the "bile duct-ligated rats". Our aim was to investigate the quantitative hepatic collagen content by two different methods during the different stages of hepatic fibrosis in bile duct-ligated rats on a weekly basis. We questioned whether the 1-wk or 4-wk bile duct-ligated model is suitable in animal fibrogenesis trials.