Quantification of Brain Atrophy in Early Multiple Sclerosis and Its Clinical Relevance

Ucar C. A. , YÜCEYAR A. N. , KİTİŞ Ö., KÖSE T., EKMEKCİ Ö., Sagduyu Kocaman A.

JOURNAL OF NEUROLOGICAL SCIENCES-TURKISH, vol.33, no.2, pp.233-243, 2016 (Journal Indexed in SCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 33 Issue: 2
  • Publication Date: 2016
  • Title of Journal : JOURNAL OF NEUROLOGICAL SCIENCES-TURKISH
  • Page Numbers: pp.233-243

Abstract

Objective Background: In multiple sclerosis (MS), axonal loss and neurodegeneration occurs early in disease course and may lead to irreversible neurological impairment. We aimed to investigate brain volume loss as an accurate measure of axonal loss and its clinical relevance in early MS.