Entecavir Treatment of Chronic Hepatitis D


Kabacam G., Onder F. O. , Yakut M., Seven G., Karatayli S. C. , Karatayli E., et al.

CLINICAL INFECTIOUS DISEASES, cilt.55, ss.645-650, 2012 (SCI İndekslerine Giren Dergi)

  • Cilt numarası: 55 Konu: 5
  • Basım Tarihi: 2012
  • Doi Numarası: 10.1093/cid/cis459
  • Dergi Adı: CLINICAL INFECTIOUS DISEASES
  • Sayfa Sayısı: ss.645-650

Özet

Background. Hepatitis D virus (HDV) requires hepatitis B surface antigen (HBsAg) to propagate infection and cause disease. Entecavir is a nucleoside analog with potent antiviral efficacy, and in the woodchuck animal model it also decreased hepatitis B virus (HBV) cccDNA and woodchuck surface antigen. The aim of this study was to investigate the efficacy of entecavir in chronic hepatitis D (CHD).