Early port-site metastasis during neoadjuvant chemotherapy in advanced stage ovarian cancer: report of two cases


ÖZMEN B., ŞÜKÜR Y. E., ATABEKOĞLU C. S., HEPER A., SÖNMEZER M., Gungor M.

JOURNAL OF GYNECOLOGIC ONCOLOGY, vol.22, no.1, pp.57-60, 2011 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 22 Issue: 1
  • Publication Date: 2011
  • Doi Number: 10.3802/jgo.2011.22.1.57
  • Journal Name: JOURNAL OF GYNECOLOGIC ONCOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.57-60
  • Keywords: Early port-site metastasis, Laparoscopy, Neoadjuvant chemotherapy, Ovarian cancer, LAPAROSCOPIC SURGERY, ABDOMINAL-WALL, CARCINOMA, IMPLANTATION, MANAGEMENT, TROCAR, RISK
  • Acibadem Mehmet Ali Aydinlar University Affiliated: Yes

Abstract

Port-site metastases in gynecological malignancies subsequent to laparoscopy have been reported with an incidence of 1.1-16%. These metastases tend to be disappearing after primary debulking surgery and subsequent primary chemotherapy. Local resection, chemotherapy and/or radiotherapy have been defined in the management of these metastases with enhanced clinical success. However, in extremely rare cases these metastases were also defined very early during neoadjuvant chemotherapy. Herein, we present two ovarian cancer cases which are clinically diagnosed with pot site metastasis during neoadjuvant chemotherapy following diagnostic laparoscopy. Although neoadjuvant chemotherapy is sometimes needed in cases of fully advanced ovarian cancers, port-site metastasis may be encountered during neoadjuvant chemotherapy. The possible poor prognosis of these patients, especially those who have ascites, should make us careful in performing diagnostic laparoscopy with preventive measures for port-site metastasis and to start the chemotherapy immediately.