Iron preloading aggravates nutritional steatohepatitis in rats by increasing apoptotic cell death


Imeryuz N., Tahan V., Sonsuz A., Eren F., Uraz S., Yuksel M., ...More

JOURNAL OF HEPATOLOGY, vol.47, no.6, pp.851-859, 2007 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 47 Issue: 6
  • Publication Date: 2007
  • Doi Number: 10.1016/j.jhep.2007.06.018
  • Title of Journal : JOURNAL OF HEPATOLOGY
  • Page Numbers: pp.851-859

Abstract

Background/Aims: High serum ferritin and liver iron concentrations were found in some patients with NASH, suggesting a role for iron as a co-factor that aggravates liver injury. The aim of this study is to investigate the effects of parenteral iron in a rat model of NASH induced by a methionine choline deficient diet (MCDD).