Atrial natriuretic peptide: Could it be a marker for postoperative recurrent effusions after Fontan circulation in complex congenital heart defects?

Alkan T., Sarioglu A., Samanli U. B., Sarioglu T., Akcevin A., Tuerkoglu H., ...More

ASAIO JOURNAL, vol.52, no.5, pp.543-548, 2006 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 52 Issue: 5
  • Publication Date: 2006
  • Doi Number: 10.1097/01.mat.0000235275.65027.1d
  • Journal Name: ASAIO JOURNAL
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.543-548
  • Acibadem Mehmet Ali Aydinlar University Affiliated: No


Fontan operation and its modifications are used for the physiological correction of complex congenital heart malformations with functionally single ventricle. Atrial natriuretic peptide (ANP), a physiological diuretic and vasodilator that-together with the effects of cardiopulmonary bypass-plays an important role in the augmentation of capillary permeability in Fontan patients. The rise in right atrial pressure and wall stress is an important stimulus for the release of ANP.