High frequency oscillations in brain hemodynamic response

AKIN A., Bolay H. B.

Conference on Diffuse Optical Imaging of Tissue, Munich, Germany, 19 - 21 June 2007, vol.6629 identifier identifier identifier

  • Publication Type: Conference Paper / Full Text
  • Volume: 6629
  • Doi Number: 10.1117/12.728233
  • City: Munich
  • Country: Germany
  • Acibadem Mehmet Ali Aydinlar University Affiliated: No


Tight autoregulation of vessel tone guarantees proper delivery of nutrients to the tissues. This regulation is maintained at a more delicate level in the brain since any decrease in the supply of glucose and oxygen to neuronal tissues might lead to unrecoverable injury. Functional near infrared spectroscopy has been proposed as a new tool to monitor the cerebrovascular response during cognitive activity. We have observed that during a Stroop task three distinct oscillatory patterns govern the control of the cerebrovascular reactivity: very low frequency (0.02-0.05 Hz), low frequency (0.08-0.12 Hz) and high frequency (0.12-0.18 Hz). High frequency oscillations have been shown to be related to stress level of the subjects. Our findings indicate that as the stress level is increased so does the energy of the high frequency component indicating a higher stimulation from the autonomic nervous system.