SOX1 antibodies are markers of paraneoplastic Lambert-Eaton myasthenic syndrome

Sabater L., Titulaer M., Saiz A., Verschuuren J., Guere A. O., Graus F.

NEUROLOGY, cilt.70, sa.12, ss.924-928, 2008 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 70 Sayı: 12
  • Basım Tarihi: 2008
  • Doi Numarası: 10.1212/01.wnl.0000281663.81079.24
  • Dergi Adı: NEUROLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.924-928
  • Acıbadem Mehmet Ali Aydınlar Üniversitesi Adresli: Hayır

Özet

Background/Objective: We reported that 43% of patients with Lambert-Eaton myasthenic syndrome (LEMS) and small cell lung cancer (SCLC) had an antibody called anti-glial nuclear antibody (AGNA), defined by the immunoreaction with the nuclei of the Bergmann glia of the cerebellum. This study was undertaken to identify the antigen recognized by AGNA and to confirm the association with paraneoplastic LEMS in a larger series.