Does Age Matter in Elder Patients Over 80 Years Undergoing Coronary Artery Bypass Grafting

İyigün M.

Journal of Cardiovascular Diseases & Diagnosis, vol.2018, no.6, pp.329-336, 2018 (Peer-Reviewed Journal)


Background: Coronary artery disease remains the most common cause of death in developing nations. Despite the associated risks of open cardiac surgery in elder patients, coronary artery bypass grafting (CABG) remains the gold Standard in treatment of patients with multiple coronary lesions. Many studies have been done to clearly determine the risks associated with early mortality after CABG in elderly patients.

Aim: To reveal the clinical experience of our center on the risks associated with mortality and morbidity in patients over 80-years-old who undergo isolated CABG.

Study design: Retrospective study.

Method: Our retrospective study consisted of 85 patients aged over 80-years who had undergone isolated coronary artery bypass grafting between January 2010 to July 2017 at our center. In this retrospective study, preoperative characteristics, operative data and postoperative outcomes were reviewed in relation to early and late mortality.

Results: Our study consisted of 85 elder patients. The mean age was 82.11 ± 2.51 years old. Early mortality was significantly higher in patients whose preoperative creatinine level was high and patients who had high level of blood transfusion (erythrocyte). No significant statistical outcome was found in patients who had early mortality in terms of preoperative hemoglobin level, cross clamping time (CCT), cardiopulmonary bypass time (CPB), body mass index (BMI) value, intensive care unit time, Ejection Fraction (%), duration of hospitalization, EuroSCORE, wound infection rate, pleural effusion rate, cerebrovascular event rate, Diabetes Mellitus (DM) rate and hypertension rate. Relevantly these factors were also associated with late mortality.

Conclusion: Preoperative high creatinine level and massive blood transfusion are associated with early and late mortality in elder patients undergoing isolated coronary artery bypass grafting.