Association between ABCB1, ABCG2 carrier protein and COX-2 enzyme gene polymorphisms and breast cancer risk in a Turkish population


Zeliha K. P. , Dilek O., Ezgi O., Halil K. , Cihan U., Gul O.

SAUDI PHARMACEUTICAL JOURNAL, cilt.28, ss.215-219, 2020 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 28 Konu: 2
  • Basım Tarihi: 2020
  • Doi Numarası: 10.1016/j.jsps.2019.11.024
  • Dergi Adı: SAUDI PHARMACEUTICAL JOURNAL
  • Sayfa Sayısı: ss.215-219

Özet

Aim: Breast cancer is the most common cancer and the second leading cause of cancer-related deaths among women. Several genetic and environmental factors are known to be involved in breast cancer pathogenesis, but the exact etiology of this disease is complicated and not completely understood. We aimed to investigate whether the gene polymorphisms of ABCB1 and ABCG2 carrier proteins and COX-2 enzyme affect breast cancer risk.