In vitro activity of a new echinocandin, LY303366, compared with those of amphotericin B and fluconazole against clinical yeast isolates


Uzun O., Kocagoz S. , Cetinkaya Y., Arikan S., Unal S.

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, cilt.41, ss.1156-1157, 1997 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 41 Konu: 5
  • Basım Tarihi: 1997
  • Doi Numarası: 10.1128/aac.41.5.1156
  • Dergi Adı: ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
  • Sayfa Sayıları: ss.1156-1157

Özet

The in vitro activity of LY303366, a new echinocandin derivative, was evaluated with 191 yeast isolates by a broth microdilution method. The MICs at which 50% of the isolates were inhibited were 0.125 mu g/ml for Candida albicans and C. tropicalis, 0.25 mu g/ml for C. krusei, C. kefyr, and C. glabrata, and 2.0 mu g/ml for C. parapsilosis.