In vitro activity of a new echinocandin, LY303366, compared with those of amphotericin B and fluconazole against clinical yeast isolates


Uzun O., Kocagoz S. , Cetinkaya Y., Arikan S., Unal S.

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, vol.41, no.5, pp.1156-1157, 1997 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 41 Issue: 5
  • Publication Date: 1997
  • Doi Number: 10.1128/aac.41.5.1156
  • Title of Journal : ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
  • Page Numbers: pp.1156-1157

Abstract

The in vitro activity of LY303366, a new echinocandin derivative, was evaluated with 191 yeast isolates by a broth microdilution method. The MICs at which 50% of the isolates were inhibited were 0.125 mu g/ml for Candida albicans and C. tropicalis, 0.25 mu g/ml for C. krusei, C. kefyr, and C. glabrata, and 2.0 mu g/ml for C. parapsilosis.