Primary cutaneous immunocytoma/marginal zone B-cell lymphoma: A case with unusual course

Demirkesen C., Tuzuner N., SU KÜÇÜK Ö., Esckazan A., Soysal T., Onsun N.

AMERICAN JOURNAL OF DERMATOPATHOLOGY, vol.26, no.2, pp.119-122, 2004 (SCI-Expanded) identifier identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 26 Issue: 2
  • Publication Date: 2004
  • Doi Number: 10.1097/00000372-200404000-00006
  • Journal Name: AMERICAN JOURNAL OF DERMATOPATHOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.119-122
  • Keywords: primary cutaneous irnmunocytoma/marginal zone B-cell lymphoma, extracutancous spread, transformation, CLASSIFICATION, PROPOSAL, SKIN
  • Acibadem Mehmet Ali Aydinlar University Affiliated: No

Abstract

Although primary cutaneous immunocytoma/marginal zone B-cell lymphoma (PCI/MZBL) is considered as an indolent lymphoma with excellent prognosis, extracutaneous spread and even death due to disseminated disease have been reported. This is a case report of a PCI/MZBL showing dissemination to the regional lymph node and bone marrow, 22 months after the initial diagnosis. Furthermore, in the lymph node, there were focal areas of high-grade transformation. On the other hand, the bone marrow involvement displayed low-grade morphology. We suggest that it should be kept in mind that there is still a possibility of systemic involvement in PCI/MZBL.